Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22684819 | 0.81 | PTPN1 (0.42) | CTSLCTSBCTSSDGAT1HDAC6 | |
| SCHEMBL22657413 | 0.79 | DEGS1 (0.42) | CTSLCTSBCTSSDGAT1DEGS1 | |
| SCHEMBL22657417 | 0.75 | MKNK1 (0.45) | CTSLCTSBCTSSNNMTDYRK1A | |
| SCHEMBL22685090 | 0.73 | CD274 (0.43) | CTSLCTSBCTSSDEGS1HDAC6 | |
| SCHEMBL22686796 | 0.72 | BTK (0.38) | CTSLCTSBCTSSHPGDHDAC6 | |
| SCHEMBL22685087 | 0.72 | CXCR3 (0.41) | CTSLCTSBCTSSDYRK1ADGAT1 | |
| SCHEMBL22685088 | 0.71 | CTSL (0.44) | CTSLCTSBCTSSDEGS1EGLN1 | |
| SCHEMBL22685305 | 0.69 | MKNK1 (0.41) | CTSLCTSBCTSSHDAC6EGLN1 | |
| SCHEMBL22685161 | 0.69 | PTPN1 (0.46) | CTSLCTSBCTSSDGAT1HDAC6 | |
| SCHEMBL22685160 | 0.69 | WDR91 (0.41) | CTSLCTSBCTSSDEGS1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |