Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 16/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 2/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685327 | 0.91 | PDE2A (0.39) | PDE2ASCN10A | |
| SCHEMBL22685324 | 0.90 | WDR91 (0.40) | PDE2ASCN10A | |
| SCHEMBL22686783 | 0.77 | WDR91 (0.42) | BTK | |
| SCHEMBL22685325 | 0.77 | PDE2A (0.39) | PDE2A | |
| SCHEMBL22684799 | 0.76 | IDO1 (0.39) | PDE2A | |
| SCHEMBL22685248 | 0.75 | PTPN1 (0.39) | PDE2ABTK | |
| SCHEMBL22685266 | 0.74 | PDE2A (0.40) | PDE2A | |
| SCHEMBL22685262 | 0.74 | WDR91 (0.40) | PDE2A | |
| SCHEMBL22685330 | 0.73 | CXCR3 (0.42) | PDE2A | |
| SCHEMBL22438947 | 0.70 | HDAC1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |