Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 7/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685266 | 0.92 | PDE2A (0.40) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685264 | 0.89 | PDE2A (0.42) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685249 | 0.88 | WDR91 (0.41) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685324 | 0.83 | WDR91 (0.40) | WDR91PDE2APTGER4PTGDRHDAC3 | |
| SCHEMBL22685329 | 0.80 | IDO1 (0.43) | HDAC3HDAC1HDAC2HDAC6MAP4K4 | |
| SCHEMBL22685078 | 0.80 | WDR91 (0.53) | WDR91PDE2AF10MAP4K4MALT1 | |
| SCHEMBL22685076 | 0.79 | PTGER4 (0.46) | WDR91PDE2APTGER4PTGDRCXCR3 | |
| SCHEMBL22686808 | 0.78 | PDE2A (0.46) | WDR91PDE2AAKT1F10MALT1 | |
| SCHEMBL22685247 | 0.78 | ROCK2 (0.41) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685250 | 0.78 | PTPN1 (0.40) | PDE2AHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |