Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 16/20 | 0.39 |
| ▸ | AKT2 | P31751 | 7/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685204 | 0.78 | AKT1 (0.41) | AKT1AKT2 | |
| SCHEMBL28488029 | 0.78 | PTGS2 (0.35) | KDM4EALDH1A1POLBSMN1; SMN2AKT1 | |
| SCHEMBL22657407 | 0.74 | CFTR (0.37) | KDM4EPOLBAKT1AKT2 | |
| SCHEMBL24910004 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16528967 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17680200 | 0.73 | KIF11 (0.52) | P2RY14 | |
| SCHEMBL22686802 | 0.73 | AKT1 (0.41) | AKT1AKT2P2RY14 | |
| SCHEMBL22685182 | 0.73 | PDE2A (0.41) | — | |
| SCHEMBL27437535 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22685206 | 0.72 | PDE2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |