SCHEMBL226863

SCHEMBL226863

OCC(O)CO[Si](O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
ALDH1A1 P00352 1/20 0.42
USP2 O75604 1/20 0.35
THRB P10828 1/20 0.35
CYP1A2 P05177 3/20 0.32
KDM4E B2RXH2 3/20 0.32
AGTR1 P30556 1/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
DUSP3 P51452 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL984836 0.80 LMNA (0.44) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL30443539 0.79 LMNA (0.38) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL6240929 0.76 LMNA (0.40) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL10818291 0.72 LMNA (0.37) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL9355138 0.72 LMNA (0.52) LMNAUSP2KDM4E
SCHEMBL1561835 0.71
Glycerin SCHEMBL11323676 0.71 LMNA (0.56) LMNAALDH1A1THRB
SCHEMBL8386335 0.70 USP2 (0.39) LMNAALDH1A1USP2CYP1A2KDM4E
SCHEMBL30754 0.69 LMNA (0.53) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL1638881 0.69 LMNA (0.53) LMNAALDH1A1USP2THRBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109354573-B Method for synthesizing long-chain fatty acid monoglyceride with high selectivity 常州大学 2021-05-25 CN claimed
CN-109456178-B Synthesis of high-content fatty acid monoglyceride and co-production of nano SiO2Method (2) 常州大学 2021-03-23 CN claimed
US-10378054-B2 Sol-gel chip using porous substrate for entrapping small molecules and screening method of small molecules specific material using thereof DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2019-08-13 US claimed
EP-2518503-B1 Sol-gel kit for preparing biochip and method for preparing biochip using the same PCL INC (KR) 2016-03-16 EP claimed
US-20160038903-A1 SOL-GEL KIT FOR PREPARING BIOCHIP AND METHODS FOR PREPARING BIOCHIP USING THE SAME PCL, INC. (KR) 2016-02-11 US claimed
US-9101902-B2 Sol-gel kit for preparing biochip and method for preparing biochip using the same PCL, INC. (KR) 2015-08-11 US claimed
US-20130210637-A1 SOL-GEL CHIP USING POROUS SUBSTRATE FOR ENTRAPPING SMALL MOLECULES AND SCREENING METHOD OF SMALL MOLECULES SPECIFIC MATERIAL USING THEREOF DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2013-08-15 US claimed
US-20120277108-A1 SOL-GEL KIT FOR PREPARING BIOCHIP AND METHOD FOR PREPARING BIOCHIP USING THE SAME PCL, INC. (KR) 2012-11-01 US claimed
EP-2518503-A1 Sol-gel kit for preparing biochip and method for preparing biochip using the same PCL, Inc. (KR) 2012-10-31 EP claimed
EP-1576042-B1 OPTICAL INFORMATION CARRIER COMPRISING IMMOBILIZED PROTEORHODOPSIN DANISCO US INC (US) 2012-05-23 EP claimed
US-7118921-B1 Incorporation and applications of biomolecular interactions within a carrier MCMASTER UNIVERSITY (CA) 2006-10-10 US claimed
US-20060121474-A1 Bio-chip prepared by gelation on a chip substrate LG CHEM, LTD (KR) 2006-06-08 US claimed
EP-1546406-A4 BIO-CHIP PREPARED BY GELATION ON A CHIP SUBSTRATE LG CHEMICAL LTD (KR) 2005-11-23 EP claimed
EP-1576042-A2 OPTICAL INFORMATION CARRIER COMPRISING IMMOBILIZED PROTEORHODOPSIN GENENCOR INTERNATIONAL, INC. (US) 2005-09-21 EP claimed
EP-1546406-A1 BIO-CHIP PREPARED BY GELATION ON A CHIP SUBSTRATE LG Chem, Ltd. (KR) 2005-06-29 EP claimed
US-20040223323-A1 Optical information carrier comprising immobilized proteorhodopsin DANISCO US INC. 2004-11-11 US claimed
WO-2004048451-A2 OPTICAL INFORMATION CARRIER COMPRISING IMMOBILIZED PROTEORHODOPSIN GENENCOR INTERNATIONAL, INC. (US) 2004-06-10 WO claimed
WO-2004024955-A1 BIO-CHIP PREPARED BY GELATION ON A CHIP SUBSTRATE LG CHEM, LTD. (KR) 2004-03-25 WO claimed
EP-1188057-A2 INCORPORATION AND APPLIATIONS OF BIOMOLECULAR INTERACTIONS WITHIN A CARRIER McMASTER UNIVERSITY (CA) 2002-03-20 EP claimed
WO-2001001139-A2 INCORPORATION AND APPLIATIONS OF BIOMOLECULAR INTERACTIONS WITHIN A CARRIER MCMASTER UNIVERSITY (CA) 2001-01-04 WO claimed