Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386335 | 0.88 | USP2 (0.39) | LMNAALDH1A1USP2CYP1A2KDM4E | |
| SCHEMBL10818291 | 0.85 | LMNA (0.37) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL226863 | 0.80 | LMNA (0.42) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL13416103 | 0.79 | LMNA (0.34) | LMNAALDH1A1USP2CYP1A2KDM4E | |
| SCHEMBL6240929 | 0.78 | LMNA (0.40) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL30443539 | 0.76 | LMNA (0.38) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL14719495 | 0.74 | TSHR (0.35) | KDM4ETSHRCSNK2A1 | |
| SCHEMBL4641295 | 0.72 | LMNA (0.40) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL1638881 | 0.71 | LMNA (0.53) | LMNAALDH1A1USP2THRBCYP1A2 | |
| SCHEMBL30754 | 0.71 | LMNA (0.53) | LMNAALDH1A1USP2THRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160106091-A1 | FREEZE PRESERVATION OF LIVING CELLS | UNIVERSITE DE NAMUR (BE) | 2016-04-21 | — | — | US | claimed |
| EP-3007554-A1 | FREEZE PRESERVATION OF LIVING CELLS | Université de Namur (BE) | 2016-04-20 | — | — | EP | claimed |
| US-20150099289-A1 | CARBONIC ANHYDRASE XEROGEL PARTICLES | CO2 SOLUTIONS INC. (CA) | 2015-04-09 | — | — | US | claimed |
| US-20150050712-A1 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS | CO2 SOLUTIONS INC. (CA) | 2015-02-19 | — | — | US | claimed |
| EP-2834355-A1 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS | Akermin, Inc. (US) | 2015-02-11 | — | — | EP | claimed |
| WO-2014198760-A1 | FREEZE PRESERVATION OF LIVING CELLS | UNIVERSITE DE NAMUR (BE) | 2014-12-18 | — | — | WO | claimed |
| US-8895280-B2 | Polysilicate-polysilicone enzyme immobilization materials | AKERMIN, INC. (US) | 2014-11-25 | — | — | US | claimed |
| US-20130267004-A1 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS | AKERMIN, INC. (US) | 2013-10-10 | — | — | US | claimed |
| WO-2013151757-A1 | POLYSILICATE-POLYSILICONE ENZYME IMMOBILIZATION MATERIALS | AKERMIN, INC. (US) | 2013-10-10 | — | — | WO | claimed |
| EP-1509533-B1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | UNIV MCMASTER (CA) | 2009-10-21 | — | — | EP | claimed |
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | claimed |
| US-20070207484-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2007-09-06 | — | — | US | claimed |
| EP-1509533-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | McMASTER UNIVERSITY (CA) | 2005-03-02 | — | — | EP | claimed |
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | MCMASTER UNIVERSITY (CA) | 2004-02-19 | — | — | US | claimed |
| WO-2003102001-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | claimed |
| EP-3204146-B1 | PROCESSES FOR CARBON DIOXIDE CAPTURE WITH BIOCATALYST RECOVERY SYSTEM | SAIPEM SPA (IT) | 2022-12-07 | — | — | EP | disclosed |
| EP-3204146-A1 | PROCESSES FOR CARBON DIOXIDE CAPTURE WITH BIOCATALYST RECOVERY SYSTEM | CO2 Solutions Inc. (CA) | 2017-08-16 | — | — | EP | disclosed |
| EP-1509533-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | McMASTER UNIVERSITY (CA) | 2005-03-02 | — | — | EP | disclosed |
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | MCMASTER UNIVERSITY (CA) | 2004-02-19 | — | — | US | disclosed |
| WO-2003102001-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | SUGT1, SORD, UGCG | LMNA 1981/4885ALDH1A1 2717/4885USP2 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.