Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686421 | 0.84 | ESR1 (0.58) | ESR1SMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL22686454 | 0.83 | ESR1 (0.63) | ESR1LMNAKMT2APOLBMEN1 | |
| SCHEMBL2728564 | 0.83 | GAA (0.69) | ESR1SMN1; SMN2MAPK1LMNAKMT2A | |
| Sulfadoxine SCHEMBL41069 | 0.74 | ESR1 (1.00) | ESR1SMN1; SMN2TSHRLMNAKMT2A | |
| Sulfadoxine SCHEMBL29390814 | 0.74 | ESR1 (1.00) | ESR1SMN1; SMN2TSHRLMNAKMT2A | |
| SCHEMBL21753107 | 0.74 | ESR1 (0.76) | ESR1LMNAKMT2AMEN1CYP19A1 | |
| SCHEMBL31548600 | 0.74 | ESR1 (0.76) | ESR1LMNAKMT2AMEN1CYP19A1 | |
| Sulfadoxine SCHEMBL28436237 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2TSHRLMNAKMT2A | |
| Sulfadoxine SCHEMBL28537335 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2TSHRLMNAKMT2A | |
| Sulfadoxine SCHEMBL28359083 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497712-B2 | Property modulation with chemical transformations | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-12-16 | — | — | US | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |