Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686308 | 0.83 | ESR1 (0.58) | GAAESR1ALDH1A1LMNASMN1; SMN2 | |
| Sulfadoxine SCHEMBL29390814 | 0.81 | ESR1 (1.00) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E | |
| Sulfadoxine SCHEMBL41069 | 0.81 | ESR1 (1.00) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9007901 | 0.81 | ESR1 (0.58) | GAAESR1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL21753107 | 0.81 | ESR1 (0.76) | ESR1LMNAKDM4ECYP19A1MEN1 | |
| SCHEMBL31548600 | 0.81 | ESR1 (0.76) | ESR1LMNAKDM4ECYP19A1MEN1 | |
| Sulfadoxine SCHEMBL28537335 | 0.80 | ESR1 (0.97) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E | |
| Sulfadoxine SCHEMBL28436237 | 0.80 | ESR1 (0.97) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E | |
| Sulfadoxine SCHEMBL28359083 | 0.80 | ESR1 (0.97) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E | |
| Sulfadoxine SCHEMBL27856131 | 0.80 | ESR1 (0.97) | ESR1ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565615-A | Preparation method of sulfadoxine derivative | 重庆康乐制药有限公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2012058298-A1 | BIOMARKERS OF REDUCED INSULIN ACTION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | WO | disclosed |