Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686308 | 0.83 | ESR1 (0.58) | ESR1CYP19A1MEN1KMT2AGAA | |
| SCHEMBL22686421 | 0.79 | ESR1 (0.58) | ESR1CYP19A1MEN1KMT2AGAA | |
| Sulfadoxine SCHEMBL29390814 | 0.78 | ESR1 (1.00) | ESR1CYP19A1MEN1KMT2AALDH1A1 | |
| Sulfadoxine SCHEMBL41069 | 0.78 | ESR1 (1.00) | ESR1CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL2728564 | 0.77 | GAA (0.69) | ESR1CYP19A1MEN1KMT2AGAA | |
| SCHEMBL21753107 | 0.77 | ESR1 (0.76) | ESR1CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL31548600 | 0.77 | ESR1 (0.76) | ESR1CYP19A1MEN1KMT2ALMNA | |
| Sulfadoxine SCHEMBL28359083 | 0.77 | ESR1 (0.97) | ESR1CYP19A1MEN1KMT2AALDH1A1 | |
| Sulfadoxine SCHEMBL28436237 | 0.77 | ESR1 (0.97) | ESR1CYP19A1MEN1KMT2AALDH1A1 | |
| Sulfadoxine SCHEMBL28537335 | 0.77 | ESR1 (0.97) | ESR1CYP19A1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497712-B2 | Property modulation with chemical transformations | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-12-16 | — | — | US | disclosed |
| EP-3973534-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | The Regents Of The University Of Michigan (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |