Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 12/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685085 | 0.80 | AKT1 (0.38) | PDE2AAKT1ABL1CXCR3BTK | |
| SCHEMBL22685306 | 0.74 | IDO1 (0.41) | PDE2AAKT1CXCR3 | |
| SCHEMBL22686780 | 0.74 | ROCK2 (0.37) | PDE2AAKT1BTK | |
| SCHEMBL22685308 | 0.74 | PDE10A (0.40) | BTK | |
| SCHEMBL22685312 | 0.73 | BTK (0.38) | PDE2AAKT1BTK | |
| SCHEMBL22685349 | 0.73 | PDE2A (0.38) | PDE2ACXCR3BTK | |
| SCHEMBL22685090 | 0.72 | CD274 (0.43) | AKT1BTK | |
| SCHEMBL22685161 | 0.72 | PTPN1 (0.46) | BTK | |
| SCHEMBL22685089 | 0.72 | PDE2A (0.43) | PDE2AAKT1TRPV1BTK | |
| SCHEMBL22657417 | 0.72 | MKNK1 (0.45) | AKT1ABL1CXCR3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |