Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | PDE2A | O00408 | 7/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685305 | 0.79 | MKNK1 (0.41) | IDO1CXCR3CTSLCTSBCTSS | |
| SCHEMBL22685303 | 0.78 | HDAC3 (0.39) | IDO1PDE2ACTSLCTSBCTSS | |
| SCHEMBL22686792 | 0.74 | PDE2A (0.43) | PDE2ACXCR3AKT1 | |
| SCHEMBL22685085 | 0.74 | AKT1 (0.38) | PDE2ACXCR3CTSLCTSBCTSS | |
| SCHEMBL22685302 | 0.69 | CTSL (0.37) | CXCR3CTSLCTSBCTSS | |
| SCHEMBL22685161 | 0.69 | PTPN1 (0.46) | IDO1CTSLCTSBCTSSHDAC1 | |
| SCHEMBL22685178 | 0.68 | CTSL (0.37) | IDO1PDE2ACTSLCTSBCTSS | |
| SCHEMBL22686796 | 0.68 | BTK (0.38) | IDO1PDE2ACTSLCTSBCTSS | |
| SCHEMBL22685090 | 0.67 | CD274 (0.43) | CTSLCTSBCTSSAKT1HDAC1 | |
| SCHEMBL22657417 | 0.66 | MKNK1 (0.45) | CXCR3CTSLCTSBCTSSAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |