Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22693556 | 0.83 | LMNA (0.64) | LMNAMAPK10KMT2AMEN1MPO | |
| SCHEMBL31359012 | 0.83 | GPR139 (0.60) | LMNAMAPK10RXFP1TSHRMAPK1 | |
| SCHEMBL31359010 | 0.83 | GPR139 (0.60) | LMNAMAPK10RXFP1TSHRMAPK1 | |
| SCHEMBL32680072 | 0.79 | CYP1A2 (0.61) | LMNAMAPK10KMT2AMEN1MPO | |
| SCHEMBL3312291 | 0.79 | CYP1A2 (0.61) | LMNAMAPK10KMT2AMEN1MPO | |
| SCHEMBL7593290 | 0.77 | MEN1 (0.77) | LMNAMAPK10KMT2AMEN1TSHR | |
| SCHEMBL31359079 | 0.77 | MAPK10 (0.58) | LMNAMAPK10KMT2AMEN1TSHR | |
| SCHEMBL11985495 | 0.75 | CYP1A2 (0.67) | KMT2AMEN1MPOTSHRMAPK1 | |
| SCHEMBL3311524 | 0.73 | ALDH1A1 (0.73) | RXFP1KMT2AMEN1MPOTSHR | |
| SCHEMBL31359061 | 0.72 | GPR139 (0.56) | RXFP1KMT2AMEN1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | S1PR2, S1PR1, S1PR3 | LMNA 1789/4885MAPK10 3471/4885RXFP1 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.