SCHEMBL2268782

SCHEMBL2268782

C=C[Si](Cl)(CCCC)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268230 0.86
SCHEMBL2271498 0.83 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL1317936 0.72 TSHR (0.38) TSHRALDH1A1
SCHEMBL1062898 0.72
SCHEMBL1314149 0.72 TSHR (0.38) TSHRALDH1A1
SCHEMBL2269105 0.69 TSHR (0.33) TSHR
SCHEMBL2102289 0.69 TSHR (0.32) TSHR
SCHEMBL4644804 0.69 TSHR (0.32) TSHR
SCHEMBL3482514 0.68 TSHR (0.35) TSHRALDH1A1
SCHEMBL3482116 0.68 TSHR (0.35) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed