SCHEMBL2268944

SCHEMBL2268944

CCN[SiH](c1ccccc1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.38
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2D6 P10635 1/20 0.32
TP53 P04637 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
SLC6A2 P23975 1/20 0.30
POLB P06746 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2103817 0.85 KCNN4 (0.33) KCNN4GAA
SCHEMBL2103508 0.80 MEN1 (0.37) MEN1ALDH1A1KMT2ACYP2D6SIGMAR1
SCHEMBL2272995 0.76 KCNN4 (0.36) KCNN4LMNAPKMTSHRCYP2D6
SCHEMBL20218966 0.74 ATM (0.31) KCNN4LMNACYP2D6
SCHEMBL2268660 0.73 KCNN4 (0.38) KCNN4LMNAALDH1A1GAATSHR
SCHEMBL2102932 0.73 KCNN4 (0.38) KCNN4LMNAALDH1A1GAATSHR
SCHEMBL2274480 0.71 KCNN4 (0.37) KCNN4LMNAGAATP53SIGMAR1
SCHEMBL2104143 0.70 KCNN4 (0.35) KCNN4LMNATP53SIGMAR1
SCHEMBL2269967 0.70 KCNN4 (0.35) KCNN4LMNACYP2D6TP53SIGMAR1
SCHEMBL2102700 0.68 KCNN4 (0.34) KCNN4ALDH1A1TSHRTP53SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed