SCHEMBL22689682

SCHEMBL22689682

C=CS(=O)(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.46
DDAH1 O94760 3/20 0.43
ARG2 P78540 4/20 0.42
ARG1 P05089 3/20 0.42
OTC P00480 1/20 0.39
PMP22 Q01453 1/20 0.39
NOS2 P35228 4/20 0.38
NOS3 P29474 2/20 0.38
NOS1 P29475 2/20 0.38
CYP1A2 P05177 2/20 0.38
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
GLA P06280 1/20 0.38
NFKB1 P19838 1/20 0.38
APEX1 P27695 1/20 0.38
CYP2C19 P33261 1/20 0.38
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9255742 0.78 GSR (0.50) GSRDDAH1ARG2ARG1OTC
SCHEMBL3385726 0.78 GRIK1 (0.39) GSRPMP22CYP1A2
Hydrochloric Acid SCHEMBL21875953 0.77 PMP22 (0.49) GSRDDAH1ARG2ARG1OTC
SCHEMBL20445992 0.73 ZDHHC20 (0.51) GSRDDAH1ARG2ARG1OTC
Lysine SCHEMBL14876567 0.73 GSR (0.69) GSRARG2ARG1PMP22NOS2
SCHEMBL6817462 0.73 ZDHHC20 (0.51) GSRDDAH1ARG2ARG1OTC
SCHEMBL10507212 0.73 ZDHHC20 (0.51) GSRDDAH1ARG2ARG1OTC
Lysine SCHEMBL14876564 0.73 GSR (0.69) GSRARG2ARG1PMP22NOS2
SCHEMBL20446016 0.73 ZDHHC20 (0.51) GSRDDAH1ARG2ARG1OTC
SCHEMBL25724508 0.73 GSR (0.48) GSRDDAH1ARG2ARG1OTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460317-B2 Genetically encoded, phage-displayed cyclic peptide library and methods of making the same THE TEXAS A&M UNIVERSITY SYSTEM (US) 2025-11-04 US disclosed
US-20230139680-A1 A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME THE TEXAS A&M UNIVERSITY SYSTEM (US) 2023-05-04 US disclosed
EP-3972625-A1 A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME The Texas A&M University System (US) 2022-03-30 EP disclosed
CN-113727725-A Genetically encoded phage-displayed cyclic peptide libraries and methods of making the same 得克萨斯A&M大学系统 2021-11-30 CN disclosed
WO-2020236146-A1 A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME THE TEXAS A&M UNIVERSITY SYSTEM (US) 2020-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139680-A1 A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME QPCTL, LNPEP, QPCT GSR 3985/4885DDAH1 1509/4885ARG2 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.