SCHEMBL20445992

SCHEMBL20445992

C=CC(=O)NCCCCC(N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.51
ZDHHC2 Q9UIJ5 1/20 0.51
DDAH1 O94760 2/20 0.51
GSR P00390 1/20 0.48
OTC P00480 1/20 0.47
ARG2 P78540 4/20 0.44
ARG1 P05089 3/20 0.44
TGM2 P21980 7/20 0.43
DPP7 Q9UHL4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6817462 1.00 ZDHHC20 (0.51) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL10507212 1.00 ZDHHC20 (0.51) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL20446016 1.00 ZDHHC20 (0.51) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL20446014 0.98 DDAH1 (0.50) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL19463086 0.95 DDAH1 (0.56) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL19463087 0.95 DDAH1 (0.56) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL19463174 0.87 ALDH1A1 (0.45) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL19463173 0.87 ALDH1A1 (0.45) ZDHHC20ZDHHC2DDAH1GSROTC
SCHEMBL20446015 0.85 TGM2 (0.50) ZDHHC20ZDHHC2DDAH1GSRTGM2
SCHEMBL20704725 0.84 GSR (0.50) DDAH1GSROTCARG2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
US-20250170216-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-05-29 US disclosed
US-20230295259-A1 Conjugated Hepcidin Mimetics PROTAGONIST THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230016396-A1 METHODS OF POLYPEPTIDE SEQUENCING Encodia, Inc. (US) 2023-01-19 US disclosed
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS BIOPHARMA AG (CH) 2022-12-29 US disclosed
EP-4051320-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS Pharma AG (CH) 2022-09-07 EP disclosed
CN-114641316-A Biocompatible polymeric drug carriers for delivery of active agents CIS制药股份公司 2022-06-17 CN disclosed
US-20210174903-A1 ENHANCED PROTEIN STRUCTURE PREDICTION USING PROTEIN HOMOLOG DISCOVERY AND CONSTRAINED DISTOGRAMS Protein Evolution Inc. (US) 2021-06-10 US disclosed
US-20210174893-A1 PROTEIN STRUCTURE PREDICTION Homodeus, Inc. (US) 2021-06-10 US disclosed
US-11008414-B2 Polymer materials for contact lens applications CIS PHARMA AG (CH) 2021-05-18 US disclosed
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS BIOPHARMA AG (CH) 2021-05-06 US disclosed
WO-2021084087-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS PHARMA AG (CH) 2021-05-06 WO disclosed
US-20210130395-A1 PROXIMITY INDUCED SITE-SPECIFIC ANTIBODY CONJUGATION WILLIAM MARSH RICE UNIVERSITY (US) 2021-05-06 US disclosed
EP-3790590-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS Pharma AG (CH) 2021-03-17 EP disclosed
US-20200283560-A1 New polymer materials for contact lens applications CIS PHARMA AG (CH) 2020-09-10 US disclosed
WO-2019215207-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS PHARMA AG (CH) 2019-11-14 WO disclosed
EP-3356433-B1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS PHARMA AG (CH) 2019-09-18 EP disclosed
EP-3356433-A1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS Pharma AG (CH) 2018-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 ZDHHC20 3427/4885ZDHHC2 1141/4885DDAH1 82/4885
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CD47, DNPEP, MSR1 ZDHHC20 4575/4885ZDHHC2 4314/4885DDAH1 473/4885
US-20230295259-A1 Conjugated Hepcidin Mimetics HAMP, VIP, HDGF ZDHHC20 727/4885ZDHHC2 683/4885DDAH1 1340/4885
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES LNPEP, PAICS, CD47 ZDHHC20 4687/4885ZDHHC2 4469/4885DDAH1 870/4885
US-20200283560-A1 New polymer materials for contact lens applications CRYAA, CRYAB, BCAT1 ZDHHC20 3848/4885ZDHHC2 4034/4885DDAH1 99/4885
US-20210130395-A1 PROXIMITY INDUCED SITE-SPECIFIC ANTIBODY CONJUGATION CD2BP2, FCGR2A, FCGR3B ZDHHC20 323/4885ZDHHC2 177/4885DDAH1 2231/4885
US-11008414-B2 Polymer materials for contact lens applications CRYAA, BCAT1, CRYAB ZDHHC20 3984/4885ZDHHC2 4069/4885DDAH1 168/4885
US-20250170216-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF ZDHHC20 1159/4885ZDHHC2 954/4885DDAH1 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.