Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.51 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | OTC | P00480 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 4/20 | 0.44 |
| ▸ | ARG1 | P05089 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 7/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445992 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL6817462 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL10507212 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL20446014 | 0.98 | DDAH1 (0.50) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL19463086 | 0.95 | DDAH1 (0.56) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL19463087 | 0.95 | DDAH1 (0.56) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL19463174 | 0.87 | ALDH1A1 (0.45) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL19463173 | 0.87 | ALDH1A1 (0.45) | ZDHHC20ZDHHC2DDAH1GSROTC | |
| SCHEMBL20446015 | 0.85 | TGM2 (0.50) | ZDHHC20ZDHHC2DDAH1GSRTGM2 | |
| SCHEMBL20704725 | 0.84 | GSR (0.50) | DDAH1GSROTCARG2ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356433-A1 | NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS | CIS Pharma AG (CH) | 2018-08-08 | — | — | EP | disclosed |