SCHEMBL2269025

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14428453	0.86	SMN1; SMN2 (0.47)	MAPTMEN1PKMKMT2AGRIK1
	SCHEMBL2271156	0.85	SMN1; SMN2 (0.45)	MAPTMEN1KMT2ASMN1; SMN2PLA2G1B
	SCHEMBL27716702	0.85	SMN1; SMN2 (0.42)	MAPTMEN1PKMKMT2AGRIK1
	SCHEMBL14428223	0.84	KDM4C (0.49)	MAPTMEN1PKMKMT2ASMN1; SMN2
	SCHEMBL4220968	0.83	KDM4C (0.51)	MAPTMEN1PKMKMT2ASMN1; SMN2
	SCHEMBL2273832	0.81	PPARG (0.54)	MAPTMEN1PKMKMT2AGRIK1
	SCHEMBL11446342	0.81	SMN1; SMN2 (0.59)	MAPTMEN1KMT2ATDP1SMN1; SMN2
	SCHEMBL4212864	0.80	KDM4C (0.50)	MAPTMEN1PKMKMT2ATDP1
	SCHEMBL13890895	0.79	NPC1 (0.48)	MAPTMEN1PKMKMT2ATDP1
	SCHEMBL4225357	0.79	KDM4C (0.47)	MAPTMEN1PKMKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.