Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554503 | 0.86 | ESR1 (0.56) | CA1CA2SRD5A2ALDH1A1CA12 | |
| SCHEMBL854364 | 0.86 | ESR1 (0.56) | CA1CA2SRD5A2ALDH1A1CA12 | |
| SCHEMBL28093622 | 0.86 | ESR1 (0.56) | CA1CA2SRD5A2ALDH1A1CA12 | |
| SCHEMBL26827 | 0.86 | ESR1 (0.56) | CA1CA2SRD5A2ALDH1A1CA12 | |
| SCHEMBL670068 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2TDP1ALDH1A1 | |
| SCHEMBL305984 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2TDP1ALDH1A1 | |
| SCHEMBL19471869 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2TDP1ALDH1A1 | |
| SCHEMBL23465057 | 0.85 | ALDH1A1 (0.47) | TDP1SRD5A2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20995949 | 0.85 | TPMT (0.47) | CA1CA2ALDH1A1ESR1ESR2 | |
| SCHEMBL8743711 | 0.85 | SMN1; SMN2 (0.45) | TP53CA1CA2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12607636-B2 | Carbene mass tagging | NORTHEASTERN UNIVERSITY (US) | 2026-04-21 | — | — | US | disclosed |
| US-20220244265-A1 | CARBENE MASS TAGGING | NORTHEASTERN UNIVERSITY | 2022-08-04 | — | — | US | disclosed |
| WO-2020237132-A1 | CARBENE MASS TAGGING | NORTHEASTERN UNIVERSITY (US) | 2020-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12607636-B2 | Carbene mass tagging | SLCO1B3, SLCO2B1, SLCO2A1 | TSHR 164/4885TP53 3429/4885CA1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.