Sugi Predict

Sugi Predict / Compounds / SCHEMBL670068

SCHEMBL670068

SCHEMBL670068

N#C/C(=C\C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ MAPK1 P28482 4/20 0.45
▸ MAPT P10636 3/20 0.45
▸ RAB9A P51151 3/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KDM4E B2RXH2 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ CA2 P00918 3/20 0.43
▸ CA4 P22748 2/20 0.43
▸ CA12 O43570 2/20 0.43
▸ CA1 P00915 2/20 0.43
▸ CA9 Q16790 2/20 0.43
▸ CA3 P07451 1/20 0.43
▸ CA6 P23280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305984 1.00 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL19471869 1.00 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
Hydrochloric Acid SCHEMBL11318740 0.98 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9468123 0.98 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9468126 0.98 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9468108 0.98 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
Ethane SCHEMBL21462500 0.96 SMN1; SMN2 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL8129608 0.89 NR4A2 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL28615780 0.89 SMN1; SMN2 (0.46) CYP1A2SMN1; SMN2MAPK1MAPTRAB9A
SCHEMBL6744132 0.88 L3MBTL1 (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776295-A Olefin reductase, coding gene, vector, engineering bacteria and application thereof 浙江工业大学 2025-04-08 — — CN disclosed
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORPORATION (CN) 2023-01-26 — — US disclosed
CN-110256522-B Tripterine cinnamate derivatives, and preparation method and application thereof 中国药科大学 2022-03-08 — — CN disclosed
WO-2021104391-A1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 鲁南制药集团股份有限公司 2021-06-03 — — WO disclosed
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 — — EP disclosed
EP-2349999-B1 ALLOSTERIC PROTEIN KINASE MODULATORS UNIV SAARLAND (DE) 2016-01-27 — — EP disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 — — US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 — — US disclosed
US-8912186-B2 Allosteric protein kinase modulators UNIVERSITAET DES SAARLANDES (DE) 2014-12-16 — — US disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 — — US disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 — — US disclosed
US-20100099736-A1 PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT CONGENIA S.R.L. (IT) 2010-04-22 — — US disclosed
WO-2010043711-A1 ALLOSTERIC PROTEIN KINASE MODULATORS UNIVERSITAET DES SAARLANDES (DE) 2010-04-22 — — WO disclosed
EP-2177510-A1 Allosteric protein kinase modulators Universität des Saarlandes (DE) 2010-04-21 — — EP disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 — — US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 — — US disclosed
US-7300932-B2 Pyrrolo[1,2-b]pyridazine derivatives JAPAN TOBACCO INC. (JP) 2007-11-27 — — US disclosed
US-7300932-B2 Pyrrolo[1,2-b]pyridazine derivatives JAPAN TOBACCO INC. (JP) 2007-11-27 — — US disclosed
US-20070027093-A1 Anorectic JAPAN TOBACCO INC. (JP) 2007-02-01 — — US disclosed
US-20070027093-A1 Anorectic JAPAN TOBACCO INC. (JP) 2007-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF PAOX, ALOX12, PNMT ALDH1A1 418/4885CYP1A2 55/4885CYP2C9 56/4885
US-20100099736-A1 PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT CYC1, MTPN, TXN2 ALDH1A1 800/4885CYP1A2 4019/4885CYP2C9 4480/4885
US-20070027093-A1 Anorectic DGAT1, DGAT2, GPR119 ALDH1A1 303/4885CYP1A2 2539/4885CYP2C9 3405/4885
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 ALDH1A1 129/4885CYP1A2 714/4885CYP2C9 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.