Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24455161 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL30498658 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL6574035 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDNPC1 | |
| SCHEMBL9578209 | 0.80 | L3MBTL1 (0.58) | ALDH1A1KDM4EMAPTMAOBADORA2A | |
| SCHEMBL6671600 | 0.78 | RAB9A (0.48) | ALDH1A1KDM4EMAPTMAOBADORA2A | |
| SCHEMBL22692020 | 0.78 | L3MBTL1 (0.47) | ALDH1A1KDM4EMAPTMAOBADORA2A | |
| SCHEMBL30481767 | 0.78 | SHBG (0.55) | ALDH1A1KDM4EMAPTMAOBHPGD | |
| SCHEMBL24459529 | 0.78 | SHBG (0.55) | ALDH1A1KDM4EMAPTMAOBHPGD | |
| SCHEMBL27833418 | 0.76 | TDP1 (0.61) | ALDH1A1KDM4EMAPTMAOBADORA2A | |
| SCHEMBL22692035 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTMAOBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| EP-3972414-A1 | FUNGICIDAL ARYL AMIDINES | Corteva Agriscience LLC (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-113613494-A | Fungicidal arylamidines | 科迪华农业科技有限责任公司 | 2021-11-05 | — | — | CN | disclosed |
| WO-2020237131-A1 | FUNGICIDAL ARYL AMIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020237131-A1 | FUNGICIDAL ARYL AMIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | ALDH1A1 105/4885KDM4E 648/4885MAPT 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.