Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 9/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402392 | 0.87 | ATAD2 (0.41) | TRPV1POLBF2ELANECTSG | |
| SCHEMBL25898318 | 0.78 | USP1 (0.38) | ALDH1A1GAABRD4USP1MEN1 | |
| SCHEMBL22402390 | 0.76 | USP1 (0.34) | USP1TRPV1LOXBMPR1BBMPR1A | |
| SCHEMBL25899645 | 0.72 | MARK3 (0.48) | ALDH1A1KMT2AF2ELANECTSG | |
| SCHEMBL26028606 | 0.69 | SRD5A1 (0.36) | TRPV1LOXBMPR1BBMPR1AACVRL1 | |
| SCHEMBL26484419 | 0.68 | CA12 (0.33) | TRPV1 | |
| SCHEMBL12639138 | 0.66 | MEN1 (0.40) | USP1MEN1KMT2A | |
| SCHEMBL27071707 | 0.65 | BRD4 (0.52) | ALDH1A1GAABRD4POLBBMPR1B | |
| SCHEMBL3831786 | 0.64 | F2 (0.60) | ALDH1A1GAABRD4MEN1KMT2A | |
| SCHEMBL14822132 | 0.64 | GSK3B (0.47) | ALDH1A1GAABRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844049-B2 | GLP-1R agonists and uses thereof | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844049-B2 | GLP-1R agonists and uses thereof | GLP1R, GPR119, GIPR | ALDH1A1 564/4885GAA 1873/4885BRD4 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.