Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 11/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22693085 | 0.78 | ALDH1A1 (0.37) | USP1BRD4ALDH1A1GAABMPR1B | |
| SCHEMBL30322638 | 0.78 | HTR2A (0.37) | HTR2AHTR2CHTR2BBMPR1BBMPR1A | |
| SCHEMBL31530544 | 0.77 | USP1 (0.36) | USP1ALDH1A1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL25898322 | 0.70 | MARK3 (0.50) | BRD4ALDH1A1MAPTKMT2A | |
| SCHEMBL14822132 | 0.69 | GSK3B (0.47) | BRD4HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL12639138 | 0.68 | MEN1 (0.40) | USP1MEN1KMT2A | |
| SCHEMBL32681230 | 0.67 | SMN1; SMN2 (0.34) | MEN1KMT2A | |
| SCHEMBL19630004 | 0.67 | BRD4 (0.35) | BRD4ALDH1A1GAABMPR1BBMPR1A | |
| SCHEMBL745614 | 0.66 | BRD4 (0.55) | BRD4ALDH1A1GAABMPR1BBMPR1A | |
| SCHEMBL27655589 | 0.66 | HTR1A (0.39) | BRD4ALDH1A1GAABMPR1BBMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |