Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 20/20 | 0.55 |
| ▸ | TNF | P01375 | 4/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22695168 | 0.77 | IL1B (0.47) | IL1BTNFNLRP3 | |
| SCHEMBL22695361 | 0.75 | IL1B (0.47) | IL1BTNFNLRP3 | |
| SCHEMBL22655123 | 0.72 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL28673713 | 0.72 | IL1B (0.81) | IL1BTNFNLRP3 | |
| SCHEMBL22655002 | 0.72 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL25797978 | 0.71 | IL1B (0.86) | IL1BTNFNLRP3 | |
| SCHEMBL31329551 | 0.71 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22654803 | 0.71 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL29508545 | 0.71 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL21016493 | 0.69 | KMO (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234715-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |