Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 20/20 | 0.47 |
| ▸ | TNF | P01375 | 4/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22670556 | 0.89 | IL1B (0.60) | IL1BTNFNLRP3 | |
| SCHEMBL22695112 | 0.77 | IL1B (0.55) | IL1BTNFNLRP3 | |
| SCHEMBL25519417 | 0.75 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL22695361 | 0.74 | IL1B (0.47) | IL1BTNFNLRP3 | |
| SCHEMBL2131597 | 0.73 | KIF11 (0.50) | — | |
| SCHEMBL10853666 | 0.71 | CNR2 (0.53) | — | |
| SCHEMBL31404964 | 0.70 | IL1B (0.60) | IL1BTNFNLRP3 | |
| SCHEMBL28289145 | 0.70 | IL1B (0.37) | IL1BTNFNLRP3 | |
| SCHEMBL22654856 | 0.70 | IL1B (0.58) | IL1BTNFNLRP3 | |
| SCHEMBL16835766 | 0.70 | CYP11B2 (0.41) | TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234715-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |