SCHEMBL2269585

SCHEMBL2269585

C=C[Si](NCC)(c1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273625 0.81 ALDH1A1 (0.31) KCNN4ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL2100179 0.74 KCNN4 (0.31) KCNN4
SCHEMBL2269062 0.73 KCNN4 (0.33) KCNN4MAPTALDH1A1
SCHEMBL2103464 0.73 KCNN4 (0.33) KCNN4MAPTALDH1A1
SCHEMBL2103177 0.71 KCNN4 (0.39) KCNN4ALDH1A1
SCHEMBL2269404 0.71 KCNN4 (0.39) KCNN4MAPTALDH1A1
SCHEMBL17798412 0.69 ALDH1A1 (0.33) MAPTALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL2100791 0.68 KCNN4 (0.36) KCNN4MAPTALDH1A1CYP2C19
SCHEMBL2102124 0.68
SCHEMBL3004847 0.68 HTT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed