SCHEMBL2269586

SCHEMBL2269586

Cc1coc2ccc(O)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
KMT2A Q03164 1/20 0.53
SIRT1 Q96EB6 5/20 0.49
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAOB P27338 3/20 0.47
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HPGD P15428 2/20 0.45
CASP3 P42574 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
SENP6 Q9GZR1 2/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SENP8 Q96LD8 1/20 0.45
LMNA P02545 1/20 0.45
NFKB1 P19838 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28047093 0.85 GSK3B (0.52) NPC1KMT2ASIRT1ALDH1A1MAOB
SCHEMBL1400551 0.83 KDM4E (0.57) NPC1KMT2AALDH1A1NPSR1MAOB
Ethoxycarbonyl Group SCHEMBL27648956 0.82 KMT2A (0.43) NPC1KMT2ASIRT1ALDH1A1TSHR
SCHEMBL4454971 0.78 ALDH1A1 (0.47) NPC1KMT2AALDH1A1TSHRMAOB
SCHEMBL789581 0.75 ALDH1A1 (0.51) KMT2AALDH1A1TSHRMAOBMAPT
SCHEMBL31231895 0.75 PTPN1 (0.50) KMT2AALDH1A1TSHRNPSR1MAOB
SCHEMBL31405756 0.75 ALDH1A1 (0.51) KMT2AALDH1A1TSHRMAOBMAPT
SCHEMBL18936105 0.75 ALDH1A1 (0.42) ALDH1A1TSHRNPSR1HPGDKDM4E
SCHEMBL2091508 0.75 PTPN1 (0.50) NPC1SIRT1ALDH1A1MAOBMAPT
SCHEMBL5341052 0.75 NPC1 (0.44) NPC1KMT2AALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US claimed
US-11326126-B2 High performing, high impact bloom accord INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2022-05-10 US claimed
CN-113122062-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
CN-104560391-B 3- methl-benzofuran -5- alcohol and its purposes in spice composition 国际香料和香精公司 2019-06-04 CN claimed
EP-2862918-B1 3-methyl-benzofuran-5-ol and its use in perfume compositions INT FLAVORS & FRAGRANCES INC (US) 2016-06-08 EP claimed
US-9212336-B2 3-methyl-benzofuran-5-ol and its use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. 2015-12-15 US claimed
CN-104560391-A 3-methyl-benzofuran-5-ol and its use in perfume compositions INT FLAVORS & FRAGRANCES INC 2015-04-29 CN claimed
US-20150111810-A1 3-METHYL-BENZOFURAN-5-OL AND ITS USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2015-04-23 US claimed
EP-2862918-A1 3-methyl-benzofuran-5-ol and its use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2015-04-22 EP claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US claimed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP claimed
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US disclosed
EP-4613832-A1 FRAGRANCE COMPOSITION AND CONSUMER PRODUCT Takasago International Corporation (JP) 2025-09-10 EP disclosed
US-20250243427-A1 PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2025-07-31 US disclosed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP disclosed
EP-1406891-A1 THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES Bayer HealthCare AG (DE) 2004-04-14 EP disclosed
WO-2003053955-A1 THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES BAYER HEALTHCARE AG (DE) 2003-07-03 WO disclosed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243427-A1 PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS FOS, HAAO, HPD NPC1 3234/4885KMT2A 1434/4885SIRT1 1036/4885
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses KRT18, CDC73, PYCR1 NPC1 4483/4885KMT2A 2090/4885SIRT1 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.