Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22697006 | 0.92 | MEN1 (0.38) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL24283687 | 0.87 | MAPK1 (0.46) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL21298740 | 0.87 | MAPK1 (0.46) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL24283624 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL21298739 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL22696874 | 0.83 | KMT2A (0.37) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL22696878 | 0.82 | MEN1 (0.36) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL24283657 | 0.82 | MEN1 (0.44) | LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28358501 | 0.82 | MEN1 (0.44) | LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL22697005 | 0.81 | MEN1 (0.39) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | SLC6A13, SLC6A11, SLC6A1 | CYP1A2 27/4885CYP3A4 11/4885GABRA1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.