SCHEMBL22698449

SCHEMBL22698449

Cc1ccccc1-c1ccc2oc3cncc(-c4nc(-c5ccccc5)cc(-c5ccccc5)n4)c3c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
CLK4 Q9HAZ1 8/20 0.38
TSHR P16473 8/20 0.38
ALDH1A1 P00352 8/20 0.38
CYP2C19 P33261 7/20 0.38
CYP3A4 P08684 7/20 0.38
CYP1A2 P05177 6/20 0.38
CYP2D6 P10635 5/20 0.38
MAPK1 P28482 4/20 0.38
CYP2C9 P11712 3/20 0.38
LMNA P02545 4/20 0.37
USP2 O75604 3/20 0.37
TP53 P04637 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 2/20 0.36
ALOX15 P16050 1/20 0.36
DHODH Q02127 1/20 0.36
TRPA1 O75762 1/20 0.36
LCK P06239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22698440 0.88 MEN1 (0.37) TSHRALDH1A1MAPK1LMNAHSD17B10
SCHEMBL22698452 0.88 MEN1 (0.37) TSHRALDH1A1MAPK1LMNAHSD17B10
SCHEMBL22698450 0.81 MYC (0.42) ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL22698273 0.80 PLA2G2A (0.38) ALDH1A1MEN1KMT2AHPGDNPC1
SCHEMBL21277163 0.79 ENPP3 (0.37) ENPP3ENPP1CLK4TSHRALDH1A1
SCHEMBL19502357 0.78 KMT2A (0.45) ALDH1A1CYP2C19CYP1A2MAPK1CYP2C9
SCHEMBL25570433 0.77 ENPP3 (0.39) ENPP3ENPP1TSHRALDH1A1CYP1A2
SCHEMBL26707754 0.77 PLA2G2A (0.42) ENPP3ALDH1A1CYP2C19CYP1A2CYP2C9
SCHEMBL19802438 0.77 PLA2G2A (0.42) ENPP3ALDH1A1CYP2C19CYP1A2CYP2C9
SCHEMBL21277242 0.76 TSHR (0.36) ENPP3ENPP1CLK4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed