SCHEMBL22698450

SCHEMBL22698450

N#Cc1ccc(-c2ccc3oc4cncc(-c5nc(-c6ccccc6)cc(-c6ccccc6)n5)c4c3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
SLC22A12 Q96S37 3/20 0.39
ABCG2 Q9UNQ0 3/20 0.39
ABCB1 P08183 2/20 0.38
ALDH1A3 P47895 1/20 0.37
PGR P06401 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ATM Q13315 1/20 0.36
MAP4K4 O95819 1/20 0.36
CYP11B2 P19099 4/20 0.36
TNKS O95271 1/20 0.36
CYP11B1 P15538 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22698452 0.91 MEN1 (0.37) PGRKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL22698440 0.91 MEN1 (0.37) PGRKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL20391912 0.86 MYC (0.46) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22698273 0.83 PLA2G2A (0.38) PGRSMN1; SMN2ALDH1A1MAP4K4
SCHEMBL22698449 0.81 ENPP3 (0.40) KDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL38666706 0.80 ABCG2 (0.41) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22329150 0.79 ABCG2 (0.42) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22329421 0.79 ABCG2 (0.42) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL25570689 0.78 SLC22A12 (0.43) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL25570439 0.78 SLC22A12 (0.43) MYCGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed