Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365807 | 0.93 | CTSK (0.50) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL7328376 | 0.93 | ALDH1A1 (0.62) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL8137300 | 0.91 | ALDH1A1 (0.50) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL8142883 | 0.91 | ALDH1A1 (0.50) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL19701701 | 0.91 | ITGB3 (0.51) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL22233607 | 0.91 | ITGB3 (0.51) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL31205826 | 0.91 | CTSK (0.53) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL22233840 | 0.91 | ITGB3 (0.51) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL12310828 | 0.91 | CTSK (0.54) | ATMCTSKCYP3A4TSHRCYP1A2 | |
| SCHEMBL25416278 | 0.89 | ATM (0.53) | ATMCTSKCYP3A4TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |