Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22698689 | 0.93 | ATM (0.56) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL8142883 | 0.90 | ALDH1A1 (0.50) | ALDH1A1GAACTSKTSHRCYP1A2 | |
| SCHEMBL8137300 | 0.90 | ALDH1A1 (0.50) | ALDH1A1GAACTSKTSHRCYP1A2 | |
| SCHEMBL29365807 | 0.87 | CTSK (0.50) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL1554010 | 0.85 | ALDH1A1 (0.60) | ALDH1A1GAACTSKTSHRCYP1A2 | |
| SCHEMBL22233607 | 0.85 | ITGB3 (0.51) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL31205826 | 0.85 | CTSK (0.53) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL22233840 | 0.85 | ITGB3 (0.51) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL12310828 | 0.85 | CTSK (0.54) | ALDH1A1CTSKTSHRCYP1A2ATM | |
| SCHEMBL19701701 | 0.85 | ITGB3 (0.51) | ALDH1A1CTSKTSHRCYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641781-B1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5478838-A | Treating hypertension, angina pectoris, asthma, improving peripheral circulation | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0641781-A1 | 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |