Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 4/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 3/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274143 | 0.86 | ROCK2 (0.44) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| SCHEMBL24701258 | 0.86 | C3AR1 (0.42) | SIRT5ROCK2C3AR1MMP2MMP9 | |
| SCHEMBL24539700 | 0.86 | C3AR1 (0.42) | SIRT5ROCK2C3AR1MMP2MMP9 | |
| SCHEMBL21897658 | 0.86 | NPY4R (0.40) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL17803625 | 0.86 | SIRT1 (0.41) | NPY4RNPY5RNPY1RSIRT5C3AR1 | |
| SCHEMBL22264483 | 0.86 | SIRT1 (0.41) | NPY4RNPY5RNPY1RSIRT5C3AR1 | |
| SCHEMBL25765429 | 0.85 | NPY5R (0.40) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| SCHEMBL15692124 | 0.84 | NMT2 (0.45) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| SCHEMBL14978855 | 0.84 | NMT2 (0.45) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| SCHEMBL23189264 | 0.83 | ITGB3 (0.42) | NPY4RNPY5RNPY1RNPY2RITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082875-B1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC (US) | 2020-11-25 | — | — | EP | disclosed |