Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349522 | 0.82 | KDM4E (0.48) | RAB9ASIGMAR1ALDH1A1KDM4EDRD2 | |
| SCHEMBL1507008 | 0.67 | LMNA (0.67) | MAPTPRMT6ALDH1A1KDM4E | |
| SCHEMBL15314577 | 0.66 | KDM4E (0.34) | GAAMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27748189 | 0.66 | HRH4 (0.41) | GAAMAPTRAB9ASIGMAR1SMN1; SMN2 | |
| SCHEMBL5745400 | 0.66 | KCNJ1 (0.61) | SIGMAR1HTR6ALDH1A1USP2HPGD | |
| SCHEMBL13232371 | 0.64 | HTR6 (0.39) | HTR6SLC6A4 | |
| SCHEMBL8302415 | 0.64 | OPRM1 (0.51) | — | |
| SCHEMBL2996786 | 0.64 | MIF (0.52) | RAB9AMIFTAAR1 | |
| SCHEMBL10591969 | 0.63 | ALDH1A1 (0.40) | GAAMAPTRAB9AMIFALDH1A1 | |
| SCHEMBL6162716 | 0.63 | LMNA (0.61) | GAAMAPTRAB9ASIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213037-A1 | A PHARMACEUTICAL INTERMEDIATE | ZAKLADY FARMACEUTYCZNE POLPHARMA S.A. (PL) | 2022-07-07 | — | — | US | disclosed |
| EP-3741744-B1 | A PHARMACEUTICAL INTERMEDIATE FOR PREPARING PIMAVANSERIN | ZAKL FARMACEUTYCZNE POLPHARMA S A (PL) | 2022-01-05 | — | — | EP | disclosed |
| WO-2020234383-A1 | A PHARMACEUTICAL INTERMEDIATE | ZAKLADY FARMACEUTYCZNE POLPHARMA S.A. (PL) | 2020-11-26 | — | — | WO | disclosed |
| EP-3741744-A1 | A PHARMACEUTICAL INTERMEDIATE | Zaklady Farmaceutyczne "Polpharma" S.A. (PL) | 2020-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213037-A1 | A PHARMACEUTICAL INTERMEDIATE | PIM1, PAH, PIM3 | GAA 648/4885MAPT 2873/4885RAB9A 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.