Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160709 | 0.91 | ALDH1A1 (0.44) | EPHX1EPHX2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22680868 | 0.80 | CNR2 (0.41) | EPHX1EPHX2MAPK1ALDH1A1GAA | |
| SCHEMBL23993618 | 0.80 | EPHX1 (0.51) | EPHX1EPHX2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17480811 | 0.78 | KCNH2 (0.41) | EPHX1EPHX2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10994631 | 0.77 | CCNT1 (0.49) | SMN1; SMN2CNR2KCNH2CCNT1CDK9 | |
| SCHEMBL21163853 | 0.74 | MAPT (0.42) | MAPK1ALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL12176285 | 0.74 | MAPT (0.42) | MAPK1ALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL11935221 | 0.73 | EPHX1 (0.46) | EPHX1EPHX2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13438910 | 0.73 | EPHX1 (0.46) | EPHX1EPHX2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25996348 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4ECNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | EPHX1 2705/4885EPHX2 3705/4885MAPK1 4572/4885 |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | EPHX1 2705/4885EPHX2 3705/4885MAPK1 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.