SCHEMBL2269971

SCHEMBL2269971

CCNCC[SiH2]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.41
ADRB2 P07550 1/20 0.39
HTR1B P28222 1/20 0.35
HTR2A P28223 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
KCNN4 O15554 1/20 0.33
SIGMAR1 Q99720 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2C19 P33261 2/20 0.32
GLA P06280 1/20 0.32
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102348 0.90 HTT (0.34) HTTADRB2KCNN4SIGMAR1
SCHEMBL2102333 0.80 CACNA2D1 (0.34) SIGMAR1TP53TSHRGAA
SCHEMBL2267934 0.78 TAAR1 (0.46) HTR1BHTR2APRMT6SIGMAR1MEN1
SCHEMBL2274476 0.78 KCNN4 (0.35) HTTADRB2HTR1BHTR2APRMT6
SCHEMBL3682860 0.75 TP53 (0.38) TP53GAA
SCHEMBL2101038 0.73 HTT (0.33) HTTADRB2KCNN4TP53GAA
SCHEMBL1274186 0.71 LTA4H (0.38) SIGMAR1MEN1KMT2ATDP1TP53
Diethylamine SCHEMBL27864499 0.70 TP53 (0.36) HTTADRB2HTR1BHTR2APRMT6
Fluoride SCHEMBL27639867 0.70 LTA4H (0.36) SIGMAR1MEN1KMT2ATDP1TP53
SCHEMBL3678757 0.70 LTA4H (0.38) SIGMAR1MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed