SCHEMBL2267934

SCHEMBL2267934

CNCC[SiH2]c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.46
ATM Q13315 1/20 0.46
HTR2A P28223 2/20 0.43
HRH1 P35367 2/20 0.43
HTR1B P28222 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HTR1D P28221 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
HRH3 Q9Y5N1 1/20 0.35
SLC6A4 P31645 1/20 0.35
LMNA P02545 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
CARM1 Q86X55 1/20 0.34
PRMT6 Q96LA8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269971 0.78 HTT (0.41) HTR2AHTR1BMEN1KMT2ASIGMAR1
SCHEMBL2102348 0.78 HTT (0.34) TAAR1ATMSIGMAR1
SCHEMBL2270138 0.76 KDM4E (0.41) TAAR1ATMHTR2AHRH1HTR1B
SCHEMBL2102333 0.75 CACNA2D1 (0.34) SIGMAR1KDM4ESLC6A4
SCHEMBL3682860 0.73 TP53 (0.38) KDM4ECYP3A4MAPTLMNAALDH1A1
SCHEMBL29926801 0.70 ALDH1A1 (0.32) L3MBTL1SIGMAR1MAPTLMNAALDH1A1
SCHEMBL1274186 0.70 LTA4H (0.38) MEN1KMT2ASIGMAR1
SCHEMBL2268970 0.70 HTR2A (0.35) TAAR1HTR2AHRH1SIGMAR1
SCHEMBL2272019 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28598231 0.69 LOXL2 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed