SCHEMBL9620899

SCHEMBL9620899

CNc1ccc(S(=O)(=O)O)cc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
PRKCI P41743 1/20 0.51
CASP6 P55212 3/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPC1 O15118 1/20 0.46
TSHR P16473 2/20 0.45
NT5E P21589 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
GAA P10253 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
NSD2 O96028 1/20 0.41
PLCG1 P19174 1/20 0.41
DNMT1 P26358 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27457985 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10PRKCICASP6CYP2C9
SCHEMBL9484070 0.85 NPC1 (0.57) ALDH1A1HSD17B10PRKCICYP2C9NPC1
SCHEMBL21589351 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL13462253 0.83 CA1 (0.55) ALDH1A1HSD17B10PRKCICYP2C9CYP2C19
SCHEMBL2253611 0.83 G6PD (0.50) ALDH1A1PRKCINPC1GAAMAPT
SCHEMBL29602916 0.83 G6PD (0.50) ALDH1A1PRKCINPC1GAAMAPT
SCHEMBL17938382 0.81 LMNA (0.49) ALDH1A1PRKCINPC1GAAPKM
SCHEMBL8592933 0.81 NPC1 (0.70) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL8981247 0.79 TIMP3 (0.51) ALDH1A1HSD17B10CASP6CYP2C9CYP2C19
SCHEMBL14364002 0.79 SNCA (0.44) ALDH1A1HSD17B10CASP6TSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581617-A1 COMPOSITIONS COMPRISING A FILM-FORMING POLYMER AND AN AROMATIC ACID OR SALT THEREOF, AND PREPARATION AND USES THEREOF Synthomer (UK) Ltd. (GB) 2019-12-18 EP disclosed
EP-0315045-B1 DOUBLE COPPER FORMAZANE REACTIVE DYES BASF Aktiengesellschaft (DE) 1992-03-04 EP disclosed
US-4973671-A Doubled copper formazan reactive dyes containing a monofluorotriazine or monochlorotriazine group BASF AKTIENGESELLSCHAFT (DE) 1990-11-27 US disclosed
EP-0315045-A2 Double copper formazane reactive dyes BASF Aktiengesellschaft (DE) 1989-05-10 EP disclosed
EP-0042204-A2 Reactive dyestuffs IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-12-23 EP disclosed