Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113822 | 0.69 | — | — | |
| SCHEMBL17563458 | 0.63 | MGLL (0.62) | ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL18212512 | 0.60 | MGLL (0.75) | ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL7932623 | 0.59 | — | — | |
| SCHEMBL151770 | 0.59 | MGLL (0.67) | ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL9679043 | 0.58 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL28846929 | 0.56 | — | — | |
| SCHEMBL17190596 | 0.56 | MGLL (0.56) | ALDH1A1LMNAHTTRAB9A | |
| Dimethylamine SCHEMBL181615 | 0.55 | MGLL (0.59) | ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL21298999 | 0.54 | POLB (0.35) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236841-A2 | ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |