Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268296 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL17104324 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1772049 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL11825468 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL12510121 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8184169 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL2268725 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL30507409 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL835056 | 0.74 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL21217185 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| CN-114929187-A | Hair treatment agent, additive and hair treatment method | 株式会社资生堂 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021141105-A1 | HAIR TREATMENT AGENT, ADDITIVE AND HAIR TREATMENT METHOD | 株式会社 資生堂 | 2021-07-15 | — | — | WO | disclosed |
| EP-2182914-B1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | disclosed |
| CN-104093390-B | Oxide hair dye | SHISEIDO CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103108621-B | Oxidation hair dye composition | SHISEIDO CO.,LTD. (JP) | 2016-01-06 | — | — | CN | disclosed |
| CN-104093390-A | Oxidation hair dye | SHISEDO CO LTD | 2014-10-08 | — | — | CN | disclosed |
| CN-103108621-A | Oxidation hair dye composition | SHISEIDO CO LTD | 2013-05-15 | — | — | CN | disclosed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | disclosed |
| US-5350424-A | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0593038-A1 | Dyestuff composition for the gradual dyeing of hair by atmospheric oxidation and process using the same | COMBE INCORPORATED (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5246466-A | 2-Nitroresorcinol with a color modifier; brown shades | HENKEL KOMMANDITGELSELLSCHAFT AUF AKTIEN (DE) | 1993-09-21 | — | — | US | disclosed |
| US-5041608-A | Dte developers | KAO CORPORATION (JP) | 1991-08-20 | — | — | US | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4104020-A | OXIDIZABLE DEVELOPER-COUPLER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4046503-A | DEVELOPER-COUPLER HAIR DYES BASED ON ALKOXY-TRIAMINO-PYRIMIDINES | HENKEL & CIE GMBH (DT) | 1977-09-06 | — | — | US | disclosed |
| US-4043750-A | OXIDATION | HENKEL & CIE GMBH (DT) | 1977-08-23 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | ALDH1A1 1097/4885KDM4E 1620/4885HPGD 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.