Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26689985 | 0.83 | POLB (0.44) | IKBKEPOLBL3MBTL1BRD4MAPT | |
| SCHEMBL23115819 | 0.76 | ALDH1A1 (0.56) | POLBMAPTTDP1NPC1RAB9A | |
| SCHEMBL24906243 | 0.76 | LMNA (0.53) | IKBKEPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL24968079 | 0.73 | L3MBTL1 (0.63) | POLBL3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL20751064 | 0.72 | POLB (0.51) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3259500 | 0.72 | IKBKE (0.47) | IKBKEPOLBL3MBTL1BRD4MAPT | |
| SCHEMBL21807727 | 0.72 | HSD17B10 (0.39) | IKBKEPOLBBRD4MAPTSMN1; SMN2 | |
| SCHEMBL9682836 | 0.71 | LMNA (0.45) | POLBL3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL22445425 | 0.70 | L3MBTL1 (0.55) | L3MBTL1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL2234851 | 0.70 | L3MBTL1 (0.56) | L3MBTL1MAPTMAPK1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | ITGB6, ITGA6, ITGAV | IKBKE 4554/4885POLB 2112/4885ENPP3 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.