SCHEMBL2270648

SCHEMBL2270648

CCC(C)[Si](NC)(c1ccccc1)C(C)CC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.35
SIGMAR1 Q99720 3/20 0.35
SLC18A2 Q05940 1/20 0.35
LMNA P02545 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TRPA1 O75762 1/20 0.32
TSHR P16473 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
ADORA1 P30542 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274648 0.84 SIGMAR1 (0.37) TAAR1SIGMAR1SLC18A2LMNAMEN1
SCHEMBL2099678 0.80 TAAR1 (0.35) TAAR1SIGMAR1SLC18A2LMNAMEN1
SCHEMBL2267663 0.79 TDP1 (0.36) TAAR1SIGMAR1SLC18A2LMNAMEN1
SCHEMBL2101254 0.77 TAAR1 (0.33) TAAR1SIGMAR1SLC18A2LMNAMEN1
SCHEMBL27848783 0.74 LMNA (0.38) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL3895956 0.74 LMNA (0.38) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL25697085 0.74 LMNA (0.38) TAAR1SIGMAR1LMNAMEN1KMT2A
SCHEMBL2275369 0.73 ALDH1A1 (0.31) TAAR1SIGMAR1SLC18A2MEN1KMT2A
SCHEMBL2103827 0.72 SIGMAR1 (0.37) TAAR1SIGMAR1SLC18A2LMNAMEN1
SCHEMBL1315271 0.71 LMNA (0.35) TAAR1SIGMAR1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed