SCHEMBL2274648

SCHEMBL2274648

CCN[Si](c1ccccc1)(C(C)CC)C(C)CC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.37
LMNA P02545 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
TRPA1 O75762 1/20 0.32
KCNN4 O15554 1/20 0.32
TAAR1 Q96RJ0 3/20 0.32
TSHR P16473 1/20 0.31
SLC18A2 Q05940 1/20 0.31
ADORA1 P30542 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270648 0.84 TAAR1 (0.35) SIGMAR1LMNAMEN1KMT2ATRPA1
SCHEMBL2269102 0.83 SIGMAR1 (0.39) SIGMAR1MEN1KMT2AHTTKCNN4
SCHEMBL2103827 0.80 SIGMAR1 (0.37) SIGMAR1LMNAMEN1KMT2AHTT
SCHEMBL2099899 0.77 SIGMAR1 (0.35) SIGMAR1LMNAMEN1KMT2AHTT
SCHEMBL2103846 0.76 SIGMAR1 (0.34) SIGMAR1LMNAMEN1KMT2AHTT
SCHEMBL27848783 0.74 LMNA (0.38) SIGMAR1LMNAMEN1KMT2ATRPA1
SCHEMBL25697085 0.74 LMNA (0.38) SIGMAR1LMNAMEN1KMT2ATRPA1
SCHEMBL3895956 0.74 LMNA (0.38) SIGMAR1LMNAMEN1KMT2ATRPA1
SCHEMBL2267447 0.73 SIGMAR1 (0.33) SIGMAR1MEN1KMT2ATRPA1TAAR1
SCHEMBL2099678 0.72 TAAR1 (0.35) SIGMAR1LMNAMEN1KMT2ATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed