SCHEMBL2270836

SCHEMBL2270836

CCc1c([SiH3])ccc(N(CC)CC)c1CC

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PSMD14 O00487 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30
GFER P55789 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH3A1 P30838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272735 0.81
SCHEMBL2269311 0.77 NPC1 (0.32) ALDH1A3MAPK1
SCHEMBL395141 0.77 ALDH1A3 (0.38) ALDH1A3ALDH1A1GAAMAPTPSMD14
SCHEMBL2272584 0.72 ALDH1A3 (0.34) ALDH1A3ALDH1A1GAAMAPTPSMD14
SCHEMBL2100023 0.72 ALDH1A3 (0.34) ALDH1A3ALDH1A1GAAMAPTPSMD14
SCHEMBL5681241 0.69 ALDH1A1 (0.35) ALDH1A3ALDH1A1GAAMAPTCYP3A4
SCHEMBL20637280 0.69 NOS3 (0.39)
SCHEMBL3316034 0.69 GABRA1 (0.32)
SCHEMBL2272625 0.68 ALDH1A3 (0.32) ALDH1A3ALDH1A1GAAMAPT
SCHEMBL2272379 0.68 ALDH1A3 (0.32) ALDH1A3ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed