SCHEMBL2270928

SCHEMBL2270928

CCC[Si](CC)(c1ccccc1)N(CC)CC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270829 0.88 TSHR (0.33) TSHR
SCHEMBL2272365 0.82 ALDH1A1 (0.31) TSHR
SCHEMBL2269308 0.81 TSHR (0.37) TSHR
SCHEMBL2104384 0.76 ALDH1A1 (0.32) TSHR
SCHEMBL2273997 0.76 MAPT (0.33) TSHR
SCHEMBL2102665 0.73 NR1H2 (0.30) TSHR
SCHEMBL2272729 0.73 ALDH1A1 (0.36) TSHR
SCHEMBL2101652 0.72
SCHEMBL9052501 0.71 ESR1 (0.35) TSHR
SCHEMBL2101242 0.71 ALDH1A1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed