Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127633 | 0.82 | TSHR (0.34) | ESR1ESR2TSHRTP53ALDH1A1 | |
| SCHEMBL10626373 | 0.79 | ESR1 (0.37) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2272577 | 0.79 | ESR1 (0.37) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2102653 | 0.79 | ESR1 (0.37) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2100019 | 0.76 | TP53 (0.36) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2102622 | 0.76 | KCNH2 (0.39) | ESR1ESR2TSHRTP53ALDH1A1 | |
| SCHEMBL2271289 | 0.76 | TP53 (0.36) | ESR1ESR2TSHRTP53ALDH1A1 | |
| SCHEMBL9979418 | 0.76 | TP53 (0.36) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2101600 | 0.76 | NR1I2 (0.36) | ESR1ESR2TSHRTP53NR1I2 | |
| SCHEMBL2272341 | 0.76 | ESR1 (0.34) | ESR1ESR2TSHRTP53NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8277292-A | — | — | None | — | — | JP | disclosed |
| JP-H08277292-A | PRODUCTION OF ORGANIC SILICON COMPOUND | SHIN ETSU CHEM CO LTD | 1996-10-22 | — | — | JP | disclosed |