Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417807 | 0.84 | TP53 (0.38) | SIGMAR1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL2272371 | 0.83 | HTR2A (0.42) | SIGMAR1KCNH2CHRM2ADRA2ACHRM1 | |
| SCHEMBL29847552 | 0.76 | TP53 (0.35) | SIGMAR1LMNA | |
| SCHEMBL2104195 | 0.76 | SIGMAR1 (0.42) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL2266534 | 0.75 | TP53 (0.31) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10318638 | 0.72 | TP53 (0.32) | LMNA | |
| SCHEMBL2272195 | 0.72 | HTR2A (0.42) | SIGMAR1SLC6A2SLC6A4MAPTCYP3A4 | |
| SCHEMBL417994 | 0.71 | LTA4H (0.38) | SIGMAR1SMN1; SMN2TSHRLTA4H | |
| SCHEMBL2272337 | 0.71 | SIGMAR1 (0.40) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL2269778 | 0.70 | HTT (0.41) | SIGMAR1SLC6A2SLC6A4TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |