Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418321 | 0.93 | LTA4H (0.38) | LTA4HPCSK9CES2CES1SMN1; SMN2 | |
| SCHEMBL9643720 | 0.91 | DNM1 (0.40) | CES2CES1SMN1; SMN2SIGMAR1TP53 | |
| SCHEMBL418038 | 0.91 | DNM1 (0.40) | CES2CES1SMN1; SMN2SIGMAR1TP53 | |
| SCHEMBL8992249 | 0.91 | CES2 (0.37) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL415280 | 0.91 | DNM1 (0.40) | CES2CES1SMN1; SMN2SIGMAR1TP53 | |
| SCHEMBL8992386 | 0.91 | DNM1 (0.40) | CES2CES1SMN1; SMN2SIGMAR1TP53 | |
| SCHEMBL9745925 | 0.90 | PTPN1 (0.34) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL706062 | 0.87 | TSHR (0.32) | TP53TSHR | |
| SCHEMBL12816111 | 0.87 | LTA4H (0.33) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL417807 | 0.85 | TP53 (0.38) | LTA4HPCSK9CES2CES1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595370-B2 | Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems | PPG B.V. (NL) | 2009-09-29 | — | — | US | claimed |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2006-06-29 | — | — | US | claimed |
| EP-1539861-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | Sigmakalon Services B.V. (NL) | 2005-06-15 | — | — | EP | claimed |
| WO-2004007591-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | SIGMAKALON SERVICES B.V. (NL) | 2004-01-22 | — | — | WO | claimed |
| EP-1380611-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SigmaKalon Group B.V. (NL) | 2004-01-14 | — | — | EP | claimed |
| WO-2001060932-A1 | ANTIFOULING PAINT COMPOSITION | J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) | 2001-08-23 | — | — | WO | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2022-05-31 | — | — | US | disclosed |
| WO-2022074177-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-14 | — | — | WO | disclosed |
| EP-3981773-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-13 | — | — | EP | disclosed |
| EP-3156403-B1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO (JP) | 2019-08-28 | — | — | EP | disclosed |
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2019-06-13 | — | — | US | disclosed |
| US-10246441-B2 | Aromatic amine derivative, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-4957989-A | ANTIFOULING AGENT FOR SHIP BOTTOMS, NONTOXIC | TOSHIBA SILICONE CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0191260-B1 | PENTACOORDINATED SILICON COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PREPARING ORGANOSILANES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-05-31 | — | — | EP | disclosed |
| EP-0104888-B1 | PROCESS FOR PREPARING 2-HYDROXY-2-PHENYLETHYLAMINES | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4617413-A | Pentacoordinate silicon complexes, the process for their preparation and their application to the preparation of organosilanes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1986-10-14 | — | — | US | disclosed |
| EP-0191260-A1 | Pentacoordinated silicon complexes, process for their preparation and their use in preparing organosilanes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1986-08-20 | — | — | EP | disclosed |
| EP-0104888-A1 | Process for preparing 2-hydroxy-2-phenylethylamines | ELI LILLY AND COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246441-B2 | Aromatic amine derivative, and organic electroluminescent element | MAOB, MAOA, NAT1 | LTA4H 2968/4885PCSK9 4867/4885PTGS2 4023/4885 |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | C1R, C9, PCBP1 | LTA4H 870/4885PCSK9 4724/4885PTGS2 3730/4885 |
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | TYR, LEF1, EFNA1 | LTA4H 2997/4885PCSK9 4781/4885PTGS2 4444/4885 |
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | TYR, LEF1, EFNA1 | LTA4H 2997/4885PCSK9 4781/4885PTGS2 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.