SCHEMBL22719907

SCHEMBL22719907

CCOC(OCC)OCC.NNC(=O)CCCCC(=O)NN

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.50
GAA P10253 2/20 0.46
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.44
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
KMT2A Q03164 3/20 0.38
FAAH O00519 2/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
DNM1 Q05193 1/20 0.37
HSP90AA1 P07900 1/20 0.36
RECQL P46063 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28214729 0.78 CTSD (0.64) CTSDGAAALDH1A1CYP1A2CYP3A4
SCHEMBL28219205 0.78 ALDH1A1 (0.62) CTSDGAAALDH1A1CYP1A2CYP3A4
SCHEMBL49856 0.78 ALDH1A1 (0.62) CTSDGAAALDH1A1CYP1A2CYP3A4
SCHEMBL402128 0.76
Urethane SCHEMBL21877936 0.76 ALOX15 (0.60) CTSDGAAALDH1A1CYP1A2CYP3A4
Ethyl Acetate SCHEMBL22719918 0.76 ALDH1A1 (0.56) CTSDGAAALDH1A1CYP1A2CYP3A4
Acetone SCHEMBL22554792 0.75 CTSD (0.59) CTSDGAAALDH1A1CYP1A2CYP3A4
Acetone SCHEMBL6392906 0.75 CTSD (0.59) CTSDGAAALDH1A1CYP1A2CYP3A4
Water SCHEMBL4942958 0.75 ALDH1A1 (0.60) CTSDGAAALDH1A1CYP1A2CYP3A4
SCHEMBL219713 0.75 ALDH1A1 (0.67) CTSDGAAALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976580-A1 PRECURSOR COMPOUNDS OF ESTER COMPOUNDS University of Guelph (CA) 2022-04-06 EP disclosed
WO-2020237378-A1 PRECURSOR COMPOUNDS OF ESTER COMPOUNDS UNIVERSITY OF GUELPH (CA) 2020-12-03 WO disclosed