Phenobarbital

Phenobarbital

SCHEMBL22719965

C=O.CCC1(c2ccccc2)C(=O)NC(=O)NC1=O

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.75
MMP9 P14780 6/20 0.75
MMP3 P08254 3/20 0.75
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
CYP1A2 P05177 1/20 0.64
POLB P06746 1/20 0.64
TSHR P16473 1/20 0.64
APEX1 P27695 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
LMNA P02545 3/20 0.58
CYP2C19 P33261 1/20 0.53
MMP13 P45452 2/20 0.50
MMP8 P22894 1/20 0.48
CACNA1F O60840 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
HTR2A P28223 1/20 0.44
HRH1 P35367 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenobarbital SCHEMBL28099657 0.96 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL2592325 0.96 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL16583 0.96 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL18825042 0.96 MMP2 (0.80) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL3475428 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL22032658 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL1322895 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL352763 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL6807467 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1
Phenobarbital SCHEMBL2120028 0.94 MMP2 (0.77) MMP2MMP9MMP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240075076-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2024-03-07 US claimed
US-11766464-B2 Method for gut mucosa preparation to enhance microbial engraftment MILIS ANTONY (AU) 2023-09-26 US claimed
CN-115297859-A Devices, compositions and methods for colonic microbiota transplantation 托马斯·朱利叶斯·波洛迪 2022-11-04 CN claimed
US-20220226399-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2022-07-21 US claimed
EP-3996727-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT Milis, Antony (AU) 2022-05-18 EP claimed
CN-114364388-A Preparation method of intestinal mucosa for enhancing microbial implantation 安东尼·米利斯 2022-04-15 CN claimed
EP-3976030-A1 DEVICES, COMPOSITIONS AND METHODS FOR COLONIC MICROBIOME ENGRAFTMENT Borody, Thomas Julius (AU) 2022-04-06 EP claimed
WO-2021003535-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2021-01-14 WO claimed
WO-2020237323-A1 DEVICES, COMPOSITIONS AND METHODS FOR COLONIC MICROBIOME ENGRAFTMENT BORODY THOMAS J (AU) 2020-12-03 WO claimed
US-20240075076-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2024-03-07 US disclosed
US-11766464-B2 Method for gut mucosa preparation to enhance microbial engraftment MILIS ANTONY (AU) 2023-09-26 US disclosed
CN-115297859-A Devices, compositions and methods for colonic microbiota transplantation 托马斯·朱利叶斯·波洛迪 2022-11-04 CN disclosed
US-20220226399-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2022-07-21 US disclosed
EP-3996727-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT Milis, Antony (AU) 2022-05-18 EP disclosed
CN-114364388-A Preparation method of intestinal mucosa for enhancing microbial implantation 安东尼·米利斯 2022-04-15 CN disclosed
EP-3976030-A1 DEVICES, COMPOSITIONS AND METHODS FOR COLONIC MICROBIOME ENGRAFTMENT Borody, Thomas Julius (AU) 2022-04-06 EP disclosed
WO-2021154954-A1 COMPOSITIONS AND METHODS FOR TREATING BIOFILMS, INFECTIONS AND PERIODONTITIS ETHEIM BIOTICS, LLC (US) 2021-08-05 WO disclosed
WO-2021003535-A1 METHOD FOR GUT MUCOSA PREPARATION TO ENHANCE MICROBIAL ENGRAFTMENT MILIS ANTONY (AU) 2021-01-14 WO disclosed
WO-2020237323-A1 DEVICES, COMPOSITIONS AND METHODS FOR COLONIC MICROBIOME ENGRAFTMENT BORODY THOMAS J (AU) 2020-12-03 WO disclosed